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Open Access
Peer-reviewed
Research Article
CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4
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Andrew M. Garrett ,
Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: andrew.garrett@wayne.edu (AMG); joshua-weiner@uiowa.edu (JAW); robert.burgess@jax.org (RWB)
Affiliations Department of Pharmacology and Department of Ophthalmology, Visual, and Anatomical Sciences, Wayne State University, Detroit, Michigan, United States of America, The Jackson Laboratory, Bar Harbor, Maine, United States of America
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Peter J. Bosch,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Biology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, United States of America
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David M. Steffen,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Biology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, United States of America
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Leah C. Fuller,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Biology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, United States of America
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Charles G. Marcucci,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Biology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, United States of America
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Alexis A. Koch,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Pharmacology and Department of Ophthalmology, Visual, and Anatomical Sciences, Wayne State University, Detroit, Michigan, United States of America
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Preeti Bais,
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation The Jackson Laboratory, Bar Harbor, Maine, United States of America
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Joshua A. Weiner ,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: andrew.garrett@wayne.edu (AMG); joshua-weiner@uiowa.edu (JAW); robert.burgess@jax.org (RWB)
Affiliation Department of Biology and Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, United States of America
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Robert W. Burgess
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: andrew.garrett@wayne.edu (AMG); joshua-weiner@uiowa.edu (JAW); robert.burgess@jax.org (RWB)
Affiliation The Jackson Laboratory, Bar Harbor, Maine, United States of America
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CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4
- Andrew M. Garrett,
- Peter J. Bosch,
- David M. Steffen,
- Leah C. Fuller,
- Charles G. Marcucci,
- Alexis A. Koch,
- Preeti Bais,
- Joshua A. Weiner,
- Robert W. Burgess
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- Published: December 26, 2019
- https://doi.org/10.1371/journal.pgen.1008554