Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation

• Gregory R. Keele ,

  Contributed equally to this work with: Gregory R. Keele, Bryan C. Quach

  Roles Conceptualization, Formal analysis, Methodology, Software, Visualization, Writing – original draft

  Affiliations Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, The Jackson Laboratory, Bar Harbor, Maine, United States of America

  http://orcid.org/0000-0002-1843-7900

  ⨯
• Bryan C. Quach ,

  Contributed equally to this work with: Gregory R. Keele, Bryan C. Quach

  Roles Formal analysis, Software, Visualization, Writing – original draft

  Affiliations Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Center for Omics Discovery and Epidemiology, Research Triangle Institute (RTI) International, Research Triangle Park, North Carolina, United States of America

  http://orcid.org/0000-0002-1094-3104

  ⨯
• Jennifer W. Israel,

  Roles Data curation

  Affiliation Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0001-8574-0937

  ⨯
• Grace A. Chappell,

  Roles Investigation

  Affiliation Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, United States of America

  http://orcid.org/0000-0002-7543-8336

  ⨯
• Lauren Lewis,

  Roles Investigation

  Affiliation Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, United States of America

  ⨯
• Alexias Safi,

  Roles Investigation

  Affiliations Department of Pediatrics, Duke University, Durham, North Carolina, United States of America, Center for Genomic and Computational Biology, Duke University, Durham, North Carolina, United States of America

  ⨯
• Jeremy M. Simon,

  Roles Data curation

  Affiliation Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0003-3906-1663

  ⨯
• Paul Cotney,

  Roles Data curation

  Affiliation Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0003-1471-2423

  ⨯
• Gregory E. Crawford,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision

  Affiliations Department of Pediatrics, Duke University, Durham, North Carolina, United States of America, Center for Genomic and Computational Biology, Duke University, Durham, North Carolina, United States of America

  ⨯
• William Valdar ,

  Roles Conceptualization, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: william.valdar@unc.edu (WV); irusyn@tamu.edu (IR); tsfurey@email.unc.edu (TSF)

  ¶‡WV, IR, and TSF also contributed equally to this work.

  Affiliations Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0002-2419-0430

  ⨯
• Ivan Rusyn ,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: william.valdar@unc.edu (WV); irusyn@tamu.edu (IR); tsfurey@email.unc.edu (TSF)

  ¶‡WV, IR, and TSF also contributed equally to this work.

  Affiliation Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, United States of America

  http://orcid.org/0000-0001-9340-7384

  ⨯
• Terrence S. Furey

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: william.valdar@unc.edu (WV); irusyn@tamu.edu (IR); tsfurey@email.unc.edu (TSF)

  ¶‡WV, IR, and TSF also contributed equally to this work.

  Affiliations Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0001-5546-9672

  ⨯