A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoels

Aneesha G. Tewari; Jared H. Owen; Christian P. Petersen; Daniel E. Wagner; Peter W. Reddien

doi:10.1371/journal.pgen.1008401

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Peer-reviewed

Research Article

A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoels

Aneesha G. Tewari,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

http://orcid.org/0000-0003-3422-1074

⨯
Jared H. Owen,

Roles Investigation, Writing – review & editing

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Christian P. Petersen,

Roles Investigation, Writing – review & editing

Current address: Department of Molecular Biosciences, Northwestern University, Evanston, United States of America

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

http://orcid.org/0000-0001-7552-6865

⨯
Daniel E. Wagner,

Roles Investigation, Writing – review & editing

Current address: Department of Systems Biology, Harvard University, Boston, Massachusetts, United States of America

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Peter W. Reddien

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

* E-mail: reddien@wi.mit.edu

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

http://orcid.org/0000-0002-5569-333X

⨯

A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoels

Aneesha G. Tewari,
Jared H. Owen,
Christian P. Petersen,
Daniel E. Wagner,
Peter W. Reddien

Published: October 18, 2019
https://doi.org/10.1371/journal.pgen.1008401

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30 Oct 2019
19:38 GMT
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Posterior Hox in acoels Posted by pmtnez on 30 Oct 2019 at 19:38 GMT

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Gene expression
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RNA interference
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Planarians
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Wnt signaling cascade
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Tails
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Epidermis
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RNA sequencing
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Gene regulation
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