Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL

• Udita Upadhyay,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America

  http://orcid.org/0000-0002-8037-6993

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• Gerald Z. Zhuang,

  Roles Formal analysis, Methodology, Project administration, Supervision

  Affiliation Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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• Luda Diatchenko,

  Roles Data curation, Methodology, Resources, Software, Visualization

  Affiliation Alan Edwards Centre for Research on Pain, McGill University Department of Anesthesiology, Montreal, Quebec, Canada

  http://orcid.org/0000-0002-1350-6727

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• Marc Parisien,

  Roles Data curation, Software

  Affiliation Alan Edwards Centre for Research on Pain, McGill University Department of Anesthesiology, Montreal, Quebec, Canada

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• Yuan Kang,

  Roles Methodology, Resources

  Affiliation Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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• Konstantinos D. Sarantopoulos,

  Roles Formal analysis, Resources

  Affiliations Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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• Eden R. Martin,

  Roles Formal analysis, Funding acquisition, Resources, Software

  Affiliations John T. MacDonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida, United States of America, John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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• Shad B. Smith,

  Roles Data curation, Formal analysis, Software

  Affiliation Center for Translational Pain Medicine, Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States of America

  http://orcid.org/0000-0002-2056-225X

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• William Maixner,

  Roles Data curation, Formal analysis, Software

  Affiliation Center for Translational Pain Medicine, Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States of America

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• Roy C. Levitt

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rlevitt@med.miami.edu

  Affiliations Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America, John T. MacDonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida, United States of America, John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

  http://orcid.org/0000-0002-6168-2274

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