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Open Access
Peer-reviewed
Research Article
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies
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Sook Wah Yee ,
Contributed equally to this work with: Sook Wah Yee, Adrian Stecula
Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, California, United States of America
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Adrian Stecula ,
Contributed equally to this work with: Sook Wah Yee, Adrian Stecula
Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, California, United States of America
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Huan-Chieh Chien,
Roles Formal analysis, Methodology, Validation, Writing – review & editing
Affiliation Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, California, United States of America
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Ling Zou,
Roles Data curation, Methodology, Writing – review & editing
Affiliation Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, California, United States of America
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Elena V. Feofanova,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
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Marjolein van Borselen,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, California, United States of America
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Kit Wun Kathy Cheung,
Roles Data curation, Writing – review & editing
Affiliation Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, California, United States of America
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Noha A. Yousri,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliations Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar, Computer and Systems Engineering, Alexandria University, Alexandria, Egypt
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Karsten Suhre,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Physiology and Biophysics, Weill Cornell Medicine-Qatar, Doha, Qatar
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Jason M. Kinchen,
Roles Data curation, Methodology, Writing – review & editing
Affiliation Metabolon, Inc, Durham, United States of America
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Eric Boerwinkle,
Roles Data curation, Formal analysis
Affiliations Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
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Roshanak Irannejad,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation The Cardiovascular Research Institute, University of California, San Francisco, California, United States of America
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Bing Yu,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
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Kathleen M. Giacomini
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: kathy.giacomini@ucsf.edu
Affiliations Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, California, United States of America, Institute for Human Genetics, University of California San Francisco, California, United States of America
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Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies
- Sook Wah Yee,
- Adrian Stecula,
- Huan-Chieh Chien,
- Ling Zou,
- Elena V. Feofanova,
- Marjolein van Borselen,
- Kit Wun Kathy Cheung,
- Noha A. Yousri,
- Karsten Suhre,
- Jason M. Kinchen
- Published: September 25, 2019
- https://doi.org/10.1371/journal.pgen.1008208
- See the preprint