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Open Access
Peer-reviewed
Research Article
VGLL4 plays a critical role in heart valve development and homeostasis
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Wei Yu ,
Contributed equally to this work with: Wei Yu, Xueyan Ma
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Xueyan Ma ,
Contributed equally to this work with: Wei Yu, Xueyan Ma
Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Jinjin Xu,
Roles Resources
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Andreas Wilhelm Heumüller,
Roles Methodology, Writing – original draft
Affiliations State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China, Institute for Cardiovascular Regeneration, Goethe-University Hospital, Frankfurt, Germany
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Zhaoliang Fei,
Roles Methodology
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Xue Feng,
Roles Methodology
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Xiaodong Wang,
Roles Methodology
Affiliation School of Life Science and Technology, ShanghaiTech University, Shanghai, China
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Kuo Liu,
Roles Methodology
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Jinhui Li,
Roles Funding acquisition, Methodology
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Guizhong Cui,
Roles Methodology
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Guangdun Peng,
Roles Methodology
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Hongbin Ji,
Roles Resources
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Jinsong Li,
Roles Resources
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Naihe Jing,
Roles Resources
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Hai Song,
Roles Resources
Affiliation Life Sciences Institute and Innovation Center for Cell Signaling Network, Zhejiang University, Hangzhou, China
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Zhiqiang Lin,
Roles Writing – review & editing
Affiliation Masonic medical research institute, Utica, NY, United States of America
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Yun Zhao,
Roles Resources
Affiliations State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China
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Zuoyun Wang ,
Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Validation, Writing – original draft
* E-mail: wangzuoyun@sibcb.ac.cn (ZW); zhoubin@sibs.ac.cn (BZ); rayzhang@sibcb.ac.cn (LZ)
Affiliation State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Bin Zhou ,
Roles Resources, Supervision, Writing – review & editing
* E-mail: wangzuoyun@sibcb.ac.cn (ZW); zhoubin@sibs.ac.cn (BZ); rayzhang@sibcb.ac.cn (LZ)
Affiliations State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China, The Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China
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Lei Zhang
Roles Funding acquisition, Supervision, Writing – review & editing
* E-mail: wangzuoyun@sibcb.ac.cn (ZW); zhoubin@sibs.ac.cn (BZ); rayzhang@sibcb.ac.cn (LZ)
Affiliations State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China
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VGLL4 plays a critical role in heart valve development and homeostasis
- Wei Yu,
- Xueyan Ma,
- Jinjin Xu,
- Andreas Wilhelm Heumüller,
- Zhaoliang Fei,
- Xue Feng,
- Xiaodong Wang,
- Kuo Liu,
- Jinhui Li,
- Guizhong Cui
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- Published: February 21, 2019
- https://doi.org/10.1371/journal.pgen.1007977