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Open Access
Peer-reviewed
Research Article
Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation
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Mary Leatham-Jensen,
Roles Investigation, Writing – review & editing
Affiliations Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
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Christopher M. Uyehara,
Roles Investigation, Writing – review & editing
Affiliations Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
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Brian D. Strahl,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
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A. Gregory Matera,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
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Robert J. Duronio,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
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Daniel J. McKay
Roles Conceptualization, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing
* E-mail: dmckay1@email.unc.edu
Affiliations Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Integrative Program for Biological and Genome Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
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Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation
- Mary Leatham-Jensen,
- Christopher M. Uyehara,
- Brian D. Strahl,
- A. Gregory Matera,
- Robert J. Duronio,
- Daniel J. McKay
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- Published: January 30, 2019
- https://doi.org/10.1371/journal.pgen.1007932