Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination

Tianpeng Zhang; Zepeng Zhang; Gong Shengzhao; Xiaocui Li; Haiying Liu; Yong Zhao

doi:10.1371/journal.pgen.1007925

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Open Access

Peer-reviewed

Research Article

Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination

Tianpeng Zhang ,

Contributed equally to this work with: Tianpeng Zhang, Zepeng Zhang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. China
⨯
Zepeng Zhang ,

Contributed equally to this work with: Tianpeng Zhang, Zepeng Zhang

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – review & editing

Affiliation MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. China
⨯
Gong Shengzhao,

Roles Data curation, Formal analysis

Affiliation School of Chemical Engineering and Technology, Guangdong Engineering Technical Research Center for Green Household Chemicals, Guangdong Industry Technical College, Guangzhou, P.R.China
⨯
Xiaocui Li,

Roles Data curation, Formal analysis, Investigation, Visualization

Affiliation MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. China
⨯
Haiying Liu,

Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

Affiliation MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. China
⨯
Yong Zhao

Roles Conceptualization, Data curation, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: zhaoy82@mail.sysu.edu.cn

Affiliations MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. China, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
⨯

Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination

Tianpeng Zhang,
Zepeng Zhang,
Gong Shengzhao,
Xiaocui Li,
Haiying Liu,
Yong Zhao

Published: February 4, 2019
https://doi.org/10.1371/journal.pgen.1007925

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DNA replication
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DNA damage
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