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Open Access
Peer-reviewed
Research Article
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers
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Kerryn Elliott ,
Contributed equally to this work with: Kerryn Elliott, Martin Boström
Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Martin Boström ,
Contributed equally to this work with: Kerryn Elliott, Martin Boström
Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Stefan Filges,
Roles Formal analysis, Investigation
Affiliations Sahlgrenska Cancer Center, Department of Pathology and Genetics, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Sweden, Department of Clinical Pathology and Genetics, Sahlgrenska University Hospital, Gothenburg, Sweden
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Markus Lindberg,
Roles Formal analysis, Investigation, Validation, Visualization
Affiliation Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Jimmy Van den Eynden,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Anders Ståhlberg,
Roles Methodology, Supervision, Writing – review & editing
Affiliations Sahlgrenska Cancer Center, Department of Pathology and Genetics, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Sweden, Department of Clinical Pathology and Genetics, Sahlgrenska University Hospital, Gothenburg, Sweden
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Anders R. Clausen,
Roles Methodology, Supervision, Writing – review & editing
Affiliation Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Erik Larsson
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: erik.larsson@gu.se
Affiliation Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers
- Kerryn Elliott,
- Martin Boström,
- Stefan Filges,
- Markus Lindberg,
- Jimmy Van den Eynden,
- Anders Ståhlberg,
- Anders R. Clausen,
- Erik Larsson
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- Published: December 26, 2018
- https://doi.org/10.1371/journal.pgen.1007849