Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations

• Farid Rajabli ,

  Contributed equally to this work with: Farid Rajabli, Gary W. Beecham, Margaret A. Pericak-Vance

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Briseida E. Feliciano,

  Roles Resources, Writing – review & editing

  Affiliation Universidad Central del Caribe, Bayamón, Puerto Rico, United States of America

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• Katrina Celis,

  Roles Resources

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Kara L. Hamilton-Nelson,

  Roles Data curation, Formal analysis

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Patrice L. Whitehead,

  Roles Resources

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Larry D. Adams,

  Roles Resources

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Parker L. Bussies,

  Roles Resources

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Clara P. Manrique,

  Roles Resources

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Alejandra Rodriguez,

  Roles Resources

  Affiliation Universidad Central del Caribe, Bayamón, Puerto Rico, United States of America

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• Vanessa Rodriguez,

  Roles Resources

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Takiyah Starks,

  Roles Resources

  Affiliation Center for Outreach in Alzheimer’s, Aging and Community Health at North Carolina A&T State University, Greensboro, North Carolina, United States of America

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• Grace E. Byfield,

  Roles Resources

  Affiliation Center for Outreach in Alzheimer’s, Aging and Community Health at North Carolina A&T State University, Greensboro, North Carolina, United States of America

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• Carolina B. Sierra Lopez,

  Roles Resources

  Affiliation Universidad Central del Caribe, Bayamón, Puerto Rico, United States of America

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• Jacob L. McCauley,

  Roles Resources, Writing – review & editing

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Heriberto Acosta,

  Roles Resources

  Affiliation Clinica de la Memoria, San Juan, Puerto Rico, United States of America

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• Angel Chinea,

  Roles Resources

  Affiliation Universidad Central del Caribe, Bayamón, Puerto Rico, United States of America

  http://orcid.org/0000-0002-2354-4911

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• Brian W. Kunkle,

  Roles Data curation

  Affiliation John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

  http://orcid.org/0000-0002-9515-5157

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• Christiane Reitz,

  Roles Resources, Writing – review & editing

  Affiliation Gertrude H. Sergievsky Center, Taub Institute for Research on the Aging Brain, Departments of Neurology, Psychiatry, and Epidemiology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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• Lindsay A. Farrer,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Departments of Medicine (Biomedical Genetics), Neurology, Ophthalmology, Epidemiology, and Biostatistics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0001-5533-4225

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• Gerard D. Schellenberg,

  Roles Data curation, Funding acquisition, Writing – review & editing

  Affiliation Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

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• Badri N. Vardarajan,

  Roles Writing – review & editing

  Affiliation Gertrude H. Sergievsky Center, Taub Institute for Research on the Aging Brain, Departments of Neurology, Psychiatry, and Epidemiology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

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• Jeffery M. Vance,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliations John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America, Dr. John T. MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Michael L. Cuccaro,

  Roles Resources, Writing – original draft

  Affiliations John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America, Dr. John T. MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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• Eden R. Martin,

  Roles Methodology, Writing – review & editing

  Affiliations John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America, Dr. John T. MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

  http://orcid.org/0000-0002-4035-9152

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• Jonathan L. Haines,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Department of Population & Quantitative Health Sciences, Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

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• Goldie S. Byrd,

  Roles Data curation, Funding acquisition

  Affiliation Center for Outreach in Alzheimer’s, Aging and Community Health at North Carolina A&T State University, Greensboro, North Carolina, United States of America

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• Gary W. Beecham ,

  Contributed equally to this work with: Farid Rajabli, Gary W. Beecham, Margaret A. Pericak-Vance

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft

  Affiliations John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America, Dr. John T. MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

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•  [ ... ],
• Margaret A. Pericak-Vance

  Contributed equally to this work with: Farid Rajabli, Gary W. Beecham, Margaret A. Pericak-Vance

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft

  * E-mail: mpericak@med.miami.edu

  Affiliations John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America, Dr. John T. MacDonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

  http://orcid.org/0000-0001-7283-8804

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