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Open Access
Peer-reviewed
Research Article
Balancing selection at a premature stop mutation in the myostatin gene underlies a recessive leg weakness syndrome in pigs
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Oswald Matika ,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing
* E-mail: oswald.matika@roslin.ed.ac.uk
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Diego Robledo,
Roles Formal analysis, Writing – review & editing
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Ricardo Pong-Wong,
Roles Conceptualization, Data curation, Formal analysis, Software
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Stephen C. Bishop †,
† Deceased.
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Valentina Riggio,
Roles Formal analysis, Writing – review & editing
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Heather Finlayson,
Roles Investigation
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Natalie R. Lowe,
Roles Investigation
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Annabelle E. Hoste,
Roles Data curation, Resources
Affiliation JSR Genetics, Southburn, Driffield, East Yorkshire, United Kingdom
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Grant A. Walling,
Roles Conceptualization, Resources, Writing – review & editing
Affiliation JSR Genetics, Southburn, Driffield, East Yorkshire, United Kingdom
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Jorge del-Pozo,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Alan L. Archibald,
Roles Conceptualization, Writing – review & editing
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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John A. Woolliams ,
Contributed equally to this work with: John A. Woolliams, Ross D. Houston
Roles Conceptualization, Formal analysis, Funding acquisition, Writing – review & editing
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Ross D. Houston
Contributed equally to this work with: John A. Woolliams, Ross D. Houston
Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing
Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, United Kingdom
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Balancing selection at a premature stop mutation in the myostatin gene underlies a recessive leg weakness syndrome in pigs
- Oswald Matika,
- Diego Robledo,
- Ricardo Pong-Wong,
- Stephen C. Bishop,
- Valentina Riggio,
- Heather Finlayson,
- Natalie R. Lowe,
- Annabelle E. Hoste,
- Grant A. Walling,
- Jorge del-Pozo
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- Published: January 30, 2019
- https://doi.org/10.1371/journal.pgen.1007759
- See the preprint