Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

• Brian E. Cade ,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bcade@bwh.harvard.edu

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America

  http://orcid.org/0000-0003-1424-0673

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• Han Chen,

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX United States of America, Center for Precision Health, School of Public Health and School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX United States of America

  http://orcid.org/0000-0002-9510-4923

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• Adrienne M. Stilp,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA United States of America

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• Tin Louie,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA United States of America

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• Sonia Ancoli-Israel,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Psychiatry, University of California, San Diego, CA, United States of America

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• Raanan Arens,

  Roles Conceptualization, Writing – review & editing

  Affiliation The Children’s Hospital at Montefiore, Division of Respiratory and Sleep Medicine, Albert Einstein College of Medicine, Bronx, NY, United States of America

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• Richard Barfield,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America

  http://orcid.org/0000-0002-6276-7704

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• Jennifer E. Below,

  Roles Data curation, Writing – review & editing

  Affiliation Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, United States of America

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• Jianwen Cai,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, United States of America

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• Matthew P. Conomos,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA United States of America

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• Daniel S. Evans,

  Roles Data curation, Writing – review & editing

  Affiliation California Pacific Medical Center Research Institute, San Francisco, CA, United States of America

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• Alexis C. Frazier-Wood,

  Roles Data curation, Writing – review & editing

  Affiliation USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, United States of America

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• Sina A. Gharib,

  Roles Data curation, Writing – review & editing

  Affiliation Computational Medicine Core, Center for Lung Biology, UW Medicine Sleep Center, Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle WA, United States of America

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• Kevin J. Gleason,

  Roles Data curation, Writing – review & editing

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Public Health Sciences, University of Chicago, Chicago, IL, United States of America

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• Daniel J. Gottlieb,

  Roles Conceptualization, Writing – review & editing

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States of America, VA Boston Healthcare System, Boston, MA, United States of America

  http://orcid.org/0000-0001-8812-8751

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• David R. Hillman,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia

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• W. Craig Johnson,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA United States of America

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• David J. Lederer,

  Roles Data curation, Writing – review & editing

  Affiliation Departments of Medicine and Epidemiology, Columbia University, New York, NY, United States of America

  http://orcid.org/0000-0001-5258-0228

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• Jiwon Lee,

  Roles Data curation, Writing – review & editing

  Affiliation Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America

  http://orcid.org/0000-0002-4079-7494

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• Jose S. Loredo,

  Roles Conceptualization, Writing – review & editing

  Affiliation Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, UC San Diego School of Medicine, La Jolla, CA, United States of America

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• Hao Mei,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Data Science, University of Mississippi Medical Center, Jackson, MS, United States of America

  ⨯
• Sutapa Mukherjee,

  Roles Data curation, Resources, Writing – review & editing

  Affiliations Sleep Health Service, Respiratory and Sleep Services, Southern Adelaide Local Health Network, Adelaide, South Australia, Adelaide Institute for Sleep Health, Flinders University, Adelaide, South Australia

  http://orcid.org/0000-0001-5021-1648

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• Sanjay R. Patel,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America

  http://orcid.org/0000-0002-9142-5172

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• Wendy S. Post,

  Roles Data curation, Writing – review & editing

  Affiliation Division of Cardiology, Johns Hopkins University, Baltimore, MD, United States of America

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• Shaun M. Purcell,

  Roles Data curation, Writing – review & editing

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America

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• Alberto R. Ramos,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, United States of America

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• Kathryn J. Reid,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Neurology, Center for Circadian and Sleep Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

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• Ken Rice,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA United States of America

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• Neomi A. Shah,

  Roles Data curation, Writing – review & editing

  Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America

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• Tamar Sofer,

  Roles Data curation, Writing – review & editing

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States of America, Department of Biostatistics, University of Washington, Seattle, WA United States of America

  http://orcid.org/0000-0001-8520-8860

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• Kent D. Taylor,

  Roles Data curation, Writing – review & editing

  Affiliation The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America

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• Timothy A. Thornton,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA United States of America

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• Heming Wang,

  Roles Data curation, Writing – review & editing

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America

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• Kristine Yaffe,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Psychiatry, Neurology, and Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, United States of America, San Francisco VA Medical Center, San Francisco, CA, United States of America

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• Phyllis C. Zee,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Neurology, Center for Circadian and Sleep Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

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• Craig L. Hanis,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliation Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX United States of America

  http://orcid.org/0000-0002-4880-5348

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• Lyle J. Palmer,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliation School of Public Health, University of Adelaide, South Australia, Australia

  http://orcid.org/0000-0002-1628-3055

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• Jerome I. Rotter,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliation The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America

  http://orcid.org/0000-0001-7191-1723

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• Katie L. Stone,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliation California Pacific Medical Center Research Institute, San Francisco, CA, United States of America

  ⨯
• Gregory J. Tranah,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliation California Pacific Medical Center Research Institute, San Francisco, CA, United States of America

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• James G. Wilson,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliation Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson MS, United States of America

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• Shamil R. Sunyaev,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliations Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America, Division of Genetics, Brigham and Women's Hospital, Boston, MA, United States of America, Division of Medical Sciences, Harvard Medical School, Boston, MA, United States of America

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• Cathy C. Laurie,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Biostatistics, University of Washington, Seattle, WA United States of America

  http://orcid.org/0000-0003-2572-4040

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• Xiaofeng Zhu,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, United States of America

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• Richa Saxena,

  Roles Conceptualization, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States of America, Center for Genomic Medicine and Department of Anesthesia, Pain, and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, United States of America

  ⨯
• Xihong Lin,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America

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•  [ ... ],
• Susan Redline

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States of America, Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America

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