Capitalizing on the heterogeneous effects of CFTR nonsense and frameshift variants to inform therapeutic strategy for cystic fibrosis

• Neeraj Sharma ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: nsharma5@jhmi.edu (NS); gcutting@jhmi.edu(GRC)

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  http://orcid.org/0000-0001-8474-3714

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• Taylor A. Evans,

  Roles Methodology, Validation

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Matthew J. Pellicore,

  Roles Investigation, Methodology, Validation

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Emily Davis,

  Roles Methodology

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Melis A. Aksit,

  Roles Methodology, Software

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Allison F. McCague,

  Roles Methodology

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Anya T. Joynt,

  Roles Methodology

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Zhongzhu Lu,

  Roles Methodology

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Sangwoo T. Han,

  Roles Methodology, Writing – review & editing

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  http://orcid.org/0000-0002-5876-704X

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• Arianna F. Anzmann,

  Roles Methodology

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Anh-Thu N. Lam,

  Roles Methodology

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Abigail Thaxton,

  Roles Methodology

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, United States of America

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• Natalie West,

  Roles Investigation

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, United States of America

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• Christian Merlo,

  Roles Investigation, Resources

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, United States of America

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• Laura B. Gottschalk,

  Roles Investigation, Resources

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Karen S. Raraigh,

  Roles Data curation, Writing – review & editing

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Patrick R. Sosnay,

  Roles Data curation, Investigation

  Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, United States of America

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• Calvin U. Cotton,

  Roles Funding acquisition, Investigation, Methodology, Writing – review & editing

  Affiliation Departments of Pediatrics, Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, United States of America

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•  [ ... ],
• Garry R. Cutting

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  * E-mail: nsharma5@jhmi.edu (NS); gcutting@jhmi.edu(GRC)

  Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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