A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer

• Tamara Zoranovic ,

  Contributed equally to this work with: Tamara Zoranovic, Jan Manent

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Current address: a Argus Consult GmbH, Berlin, Germany

  Affiliation IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria

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• Jan Manent ,

  Contributed equally to this work with: Tamara Zoranovic, Jan Manent

  Roles Conceptualization, Formal analysis, Investigation, Validation, Writing – review & editing

  Current address: b Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia

  Affiliations Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia, Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

  http://orcid.org/0000-0001-9152-5459

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• Lee Willoughby,

  Roles Investigation, Validation, Visualization

  Affiliation Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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• Ricardo Matos de Simoes,

  Roles Formal analysis

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0002-1700-5276

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• John E. La Marca,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

  http://orcid.org/0000-0001-6442-9947

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• Sofya Golenkina,

  Roles Investigation, Visualization

  Affiliation Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia

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• Xia Cuiping,

  Roles Investigation

  Affiliation IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria

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• Susanne Gruber,

  Roles Investigation

  Affiliation IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria

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• Belinda Angjeli,

  Roles Investigation

  Affiliation IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria

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• Elisabeth Eva Kanitz,

  Roles Investigation

  Affiliation IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria

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• Shane J. F. Cronin,

  Roles Investigation

  Affiliation IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria

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• G. Gregory Neely,

  Roles Investigation

  Affiliations IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria, The Charles Perkins Centre, School of Life & Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia

  http://orcid.org/0000-0003-2809-6457

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• Andreas Wernitznig,

  Roles Formal analysis

  Affiliation Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria

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• Patrick O. Humbert,

  Roles Conceptualization, Supervision

  Affiliations Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia, Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia, Sir Peter MacCallum Department of Oncology, Department of Anatomy & Neuroscience, Department of Biochemistry & Molecular Biology, and Department of Clinical Pathology, University of Melbourne, Melbourne, Victoria, Australia

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• Kaylene J. Simpson,

  Roles Supervision

  Affiliations Sir Peter MacCallum Department of Oncology, Department of Anatomy & Neuroscience, Department of Biochemistry & Molecular Biology, and Department of Clinical Pathology, University of Melbourne, Melbourne, Victoria, Australia, Victorian Center for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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• Constantine S. Mitsiades,

  Roles Formal analysis, Supervision

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

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• Helena E. Richardson ,

  Roles Conceptualization, Funding acquisition, Supervision, Validation, Writing – review & editing

  * E-mail: H.Richardson@latrobe.edu.au (HER); josef.penninger@imba.oeaw.ac.at (JMP)

  Affiliations Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia, Department of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia, Sir Peter MacCallum Department of Oncology, Department of Anatomy & Neuroscience, Department of Biochemistry & Molecular Biology, and Department of Clinical Pathology, University of Melbourne, Melbourne, Victoria, Australia

  http://orcid.org/0000-0003-3852-4953

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•  [ ... ],
• Josef M. Penninger

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: H.Richardson@latrobe.edu.au (HER); josef.penninger@imba.oeaw.ac.at (JMP)

  Affiliation IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Science, Campus Vienna BioCentre, Vienna, Austria

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