Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma

• Lana Hamieh,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America

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• Toni K. Choueiri ,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  * E-mail: toni_choueiri@dfci.harvard.edu (TKC); ssignoretti@partners.org (SS); dk@rics.bwh.harvard.edu (DJK)

  Affiliations Department of Medicine, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States of America

  http://orcid.org/0000-0002-9201-3217

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• Barbara Ogórek,

  Roles Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliations Department of Medicine, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America

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• Damir Khabibullin,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Department of Medicine, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America

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• Daniel Rosebrock,

  Roles Formal analysis, Visualization, Writing – review & editing

  Affiliation Cancer Program, Broad Institute of Harvard and MIT, Cambridge, MA, United States of America

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• Dimitri Livitz,

  Roles Formal analysis, Writing – review & editing

  Affiliation Cancer Program, Broad Institute of Harvard and MIT, Cambridge, MA, United States of America

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• Andre Fay,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations Department of Medicine, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medical Oncology, PUCRS School of Medicine, Porto Alegre, Brazil

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• Jean-Christophe Pignon,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Medicine, Harvard Medical School, Boston, MA, United States of America, Department of Pathology, Brigham and Women’s Hospital, Boston, MA, United States of America

  http://orcid.org/0000-0002-9627-4078

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• David F. McDermott,

  Roles Formal analysis, Funding acquisition, Writing – review & editing

  Affiliations Department of Medicine, Harvard Medical School, Boston, MA, United States of America, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America

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• Neeraj Agarwal,

  Roles Writing – review & editing

  Affiliation Division of Medical Oncology, University of Utah Huntsman Cancer Institute, Salt Lake City, UT, United States of America

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• Wenhua Gao,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Medicine, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States of America

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• Sabina Signoretti ,

  Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

  * E-mail: toni_choueiri@dfci.harvard.edu (TKC); ssignoretti@partners.org (SS); dk@rics.bwh.harvard.edu (DJK)

  Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States of America, Department of Pathology, Brigham and Women’s Hospital, Boston, MA, United States of America

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• David J. Kwiatkowski

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: toni_choueiri@dfci.harvard.edu (TKC); ssignoretti@partners.org (SS); dk@rics.bwh.harvard.edu (DJK)

  Affiliations Department of Medicine, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States of America

  http://orcid.org/0000-0002-5668-5219

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