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Open Access
Peer-reviewed
Research Article
E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo
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Xue Wang ,
Contributed equally to this work with: Xue Wang, Baijun Dong
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Baijun Dong ,
Contributed equally to this work with: Xue Wang, Baijun Dong
Roles Investigation, Resources, Writing – review & editing
Affiliation Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Kai Zhang,
Roles Data curation
Affiliation School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Zhongzhong Ji,
Roles Data curation, Software
Affiliation School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Chaping Cheng,
Roles Data curation, Validation
Affiliation School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Huifang Zhao,
Roles Software, Supervision
Affiliation School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Yaru Sheng,
Roles Data curation
Affiliation School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Xiaoxia Li,
Roles Resources
Affiliation School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Liancheng Fan,
Roles Resources
Affiliation Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Wei Xue,
Roles Resources
Affiliation Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Wei-Qiang Gao ,
Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing
* E-mail: gao.weiqiang@sjtu.edu.cn (W-QG); zhuhecrane@shsmu.edu.cn (HHZ)
Affiliations State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China
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Helen He Zhu
Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: gao.weiqiang@sjtu.edu.cn (W-QG); zhuhecrane@shsmu.edu.cn (HHZ)
Affiliations State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo
- Xue Wang,
- Baijun Dong,
- Kai Zhang,
- Zhongzhong Ji,
- Chaping Cheng,
- Huifang Zhao,
- Yaru Sheng,
- Xiaoxia Li,
- Liancheng Fan,
- Wei Xue
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- Published: August 17, 2018
- https://doi.org/10.1371/journal.pgen.1007609