High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor

• Tetsuji Yamashita ,

  Contributed equally to this work with: Tetsuji Yamashita, Fei Zheng

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

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• Fei Zheng ,

  Contributed equally to this work with: Tetsuji Yamashita, Fei Zheng

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  http://orcid.org/0000-0002-7020-918X

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• David Finkelstein,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Software, Validation, Visualization

  Affiliation Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  ⨯
• Zoe Kellard,

  Roles Investigation

  Affiliation Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  ⨯
• Robert Carter,

  Roles Data curation, Formal analysis, Methodology, Validation, Visualization

  Affiliation Department of Oncology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  ⨯
• Celeste D. Rosencrance,

  Roles Investigation

  Affiliation Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  http://orcid.org/0000-0001-7898-233X

  ⨯
• Ken Sugino,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Validation, Visualization

  Affiliation Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

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• John Easton,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Software, Validation, Visualization

  Affiliation Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

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• Charles Gawad ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: charles.gawad@stjude.org (CG); jian.zuo@stjude.org, jianzuo@creighton.edu (JZ)

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Department of Oncology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  ⨯
• Jian Zuo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: charles.gawad@stjude.org (CG); jian.zuo@stjude.org, jianzuo@creighton.edu (JZ)

  Current address: Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, Nebraska, United States of America

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  http://orcid.org/0000-0002-1448-4507

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