Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network

• Matthew J. Culyba ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: matthew.culyba@pitt.edu

  Current address: Department of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, United States of America

  Affiliation Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America

  http://orcid.org/0000-0001-8327-4135

  ⨯
• Jeffrey M. Kubiak ,

  Contributed equally to this work with: Jeffrey M. Kubiak, Charlie Y. Mo

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America

  http://orcid.org/0000-0002-0124-7545

  ⨯
• Charlie Y. Mo ,

  Contributed equally to this work with: Jeffrey M. Kubiak, Charlie Y. Mo

  Roles Investigation, Methodology, Writing – review & editing

  Current address: Laboratory of Bacteriology, The Rockefeller University, New York, NY, United States of America

  Affiliation Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America

  ⨯
• Mark Goulian,

  Roles Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Biology, University of Pennsylvania, Philadelphia, PA, United States of America

  http://orcid.org/0000-0003-0076-023X

  ⨯
• Rahul M. Kohli

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America, Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, United States of America

  http://orcid.org/0000-0002-7689-5678

  ⨯