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Open Access
Peer-reviewed
Research Article
Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions
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Zhijia Tan ,
Contributed equally to this work with: Zhijia Tan, Ben Niu
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing
Affiliation School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong
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Ben Niu ,
Contributed equally to this work with: Zhijia Tan, Ben Niu
Roles Conceptualization, Data curation, Formal analysis, Software, Writing – original draft, Writing – review & editing
Affiliation School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong
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Kwok Yeung Tsang,
Roles Conceptualization, Writing – review & editing
Affiliation School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong
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Ian G. Melhado,
Roles Conceptualization, Methodology, Writing – review & editing
Affiliation School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong
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Shinsuke Ohba,
Roles Data curation, Methodology, Writing – review & editing
Current address: Department of Bioengineering, the University of Tokyo, Tokyo, Japan;
Affiliation Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
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Xinjun He,
Roles Data curation, Methodology, Writing – review & editing
Affiliation Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
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Yongheng Huang,
Roles Data curation, Writing – review & editing
Current address: Group Structure Biochemistry, Institute for Chemistry and Biochemistry, Free University Berlin, Berlin, Germany
Affiliation Genome Regulation Laboratory, Guangzhou Institutes of Biomedicine and Health, Guangzhou, China
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Cheng Wang,
Roles Data curation, Methodology
Affiliation School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong
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Andrew P. McMahon,
Roles Data curation, Writing – review & editing
Affiliation Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
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Ralf Jauch,
Roles Data curation, Writing – review & editing
Affiliation Genome Regulation Laboratory, Guangzhou Institutes of Biomedicine and Health, Guangzhou, China
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Danny Chan,
Roles Conceptualization, Data curation, Project administration, Supervision, Writing – review & editing
Affiliation School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong
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Michael Q. Zhang,
Roles Conceptualization, Data curation, Methodology, Project administration, Software, Supervision, Writing – review & editing
Affiliations Department of Biological Sciences, Center for Systems Biology, The University of Texas at Dallas, Dallas, Texas, United States of America, MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, TNLIST, Tsinghua University, Beijing, China
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Kathryn S. E. Cheah
Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: kathycheah@hku.hk
Affiliation School of Biomedical Sciences, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong
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Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions
- Zhijia Tan,
- Ben Niu,
- Kwok Yeung Tsang,
- Ian G. Melhado,
- Shinsuke Ohba,
- Xinjun He,
- Yongheng Huang,
- Cheng Wang,
- Andrew P. McMahon,
- Ralf Jauch
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- Published: April 16, 2018
- https://doi.org/10.1371/journal.pgen.1007346