Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC

Ofelia Tacchelly-Benites; Zhenghan Wang; Eungi Yang; Hassina Benchabane; Ai Tian; Michael P. Randall; Yashi Ahmed

doi:10.1371/journal.pgen.1007178

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Open Access

Peer-reviewed

Research Article

Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC

Ofelia Tacchelly-Benites,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America
⨯
Zhenghan Wang,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America
⨯
Eungi Yang,

Roles Formal analysis, Investigation, Methodology, Validation, Visualization

Affiliation Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America
⨯
Hassina Benchabane,

Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America

http://orcid.org/0000-0003-0771-2249

⨯
Ai Tian,

Roles Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

Affiliation Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America
⨯
Michael P. Randall,

Roles Formal analysis, Investigation, Methodology, Validation, Visualization

Affiliation Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America
⨯
Yashi Ahmed

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: yfa@dartmouth.edu

Affiliation Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, United States of America

http://orcid.org/0000-0002-7472-6010

⨯

Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC

Ofelia Tacchelly-Benites,
Zhenghan Wang,
Eungi Yang,
Hassina Benchabane,
Ai Tian,
Michael P. Randall,
Yashi Ahmed

Published: February 6, 2018
https://doi.org/10.1371/journal.pgen.1007178

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Antigen-presenting cells
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Phosphorylation
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Wnt signaling cascade
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Drosophila melanogaster
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Immunoblotting
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ADP-ribosylation
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Phosphatases
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Larvae
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