Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites

• Xiao P. Peng ,

  Contributed equally to this work with: Xiao P. Peng, Shelly Lim

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America, Tri-Institutional MD-PhD Program of Weill Cornell Medical School, Rockefeller University, and Sloan-Kettering Cancer Center, New York, NY, United States of America

  http://orcid.org/0000-0002-7738-1150

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• Shelly Lim ,

  Contributed equally to this work with: Xiao P. Peng, Shelly Lim

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – review & editing

  Affiliation Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America

  http://orcid.org/0000-0003-0051-3132

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• Shibai Li,

  Roles Data curation, Investigation

  Affiliation Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America

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• Lisette Marjavaara,

  Roles Data curation, Formal analysis

  Affiliation Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

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• Andrei Chabes,

  Roles Data curation, Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Department of Medical Biochemistry and Biophysics, Umeå University, Umeå, Sweden

  http://orcid.org/0000-0003-1708-8259

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• Xiaolan Zhao

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: zhaox1@mskcc.org

  Affiliation Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America

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