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Open Access
Peer-reviewed
Research Article
Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH)
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Jinsung Yang ,
Contributed equally to this work with: Jinsung Yang, Min Ju Kim
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation National Creative Research Initiatives Center for Energy Homeostasis Regulation, School of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea
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Min Ju Kim ,
Contributed equally to this work with: Jinsung Yang, Min Ju Kim
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology
Affiliation Department of Pharmacology, Peripheral Neuropathy Research Center (PNRC), Dong-A University College of Medicine, Busan, Republic of Korea
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Woongchang Yoon,
Roles Data curation, Formal analysis, Investigation, Software
Affiliation National Creative Research Initiatives Center for Energy Homeostasis Regulation, School of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea
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Eun Young Kim,
Roles Data curation, Formal analysis, Investigation, Resources
Affiliation Department of Pharmacology, Peripheral Neuropathy Research Center (PNRC), Dong-A University College of Medicine, Busan, Republic of Korea
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Hyunjin Kim,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation Department of Pharmacology, Peripheral Neuropathy Research Center (PNRC), Dong-A University College of Medicine, Busan, Republic of Korea
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Yoonjeong Lee,
Roles Data curation, Investigation
Affiliation Department of Pharmacology, Peripheral Neuropathy Research Center (PNRC), Dong-A University College of Medicine, Busan, Republic of Korea
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Boram Min,
Roles Resources
Affiliation National Creative Research Initiatives Center for Energy Homeostasis Regulation, School of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea
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Kyung Shin Kang,
Roles Writing – review & editing
Affiliation National Creative Research Initiatives Center for Energy Homeostasis Regulation, School of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea
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Jin H. Son,
Roles Methodology, Resources, Supervision
Affiliation Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea
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Hwan Tae Park,
Roles Investigation, Methodology, Supervision, Validation
Affiliation Department of Physiology, Peripheral Neuropathy Research Center (PNRC), Dong-A University College of Medicine, Busan, Republic of Korea
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Jongkyeong Chung ,
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: hjkoh@dau.ac.kr (HK); jkc@snu.ac.kr (JC)
Affiliation National Creative Research Initiatives Center for Energy Homeostasis Regulation, School of Biological Sciences and Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea
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Hyongjong Koh
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: hjkoh@dau.ac.kr (HK); jkc@snu.ac.kr (JC)
Affiliation Department of Pharmacology, Peripheral Neuropathy Research Center (PNRC), Dong-A University College of Medicine, Busan, Republic of Korea
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Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH)
- Jinsung Yang,
- Min Ju Kim,
- Woongchang Yoon,
- Eun Young Kim,
- Hyunjin Kim,
- Yoonjeong Lee,
- Boram Min,
- Kyung Shin Kang,
- Jin H. Son,
- Hwan Tae Park
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- Published: August 21, 2017
- https://doi.org/10.1371/journal.pgen.1006975