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Open Access
Peer-reviewed
Research Article
A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways
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Michael Crompton,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliations Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, Oxfordshire, United Kingdom
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Tom Purnell,
Roles Investigation
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Hayley E. Tyrer,
Roles Investigation
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Andrew Parker,
Roles Investigation, Methodology, Resources
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Greg Ball,
Roles Investigation
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Rachel E. Hardisty-Hughes,
Roles Investigation
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Richard Gale,
Roles Investigation
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Debbie Williams,
Roles Investigation, Methodology, Resources
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Charlotte H. Dean,
Roles Methodology, Supervision, Writing – review & editing
Affiliations Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom, Inflammation, Repair and Development Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom
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Michelle M. Simon,
Roles Formal analysis, Methodology
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Ann-Marie Mallon,
Roles Resources
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Sara Wells,
Roles Resources
Affiliation Mary Lyon Centre, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Mahmood F. Bhutta,
Roles Funding acquisition
Affiliations Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, Oxfordshire, United Kingdom, School of Paediatrics, University of Western Australia, Subiaco, Australia
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Martin J. Burton,
Roles Funding acquisition
Affiliation Nuffield Department of Surgical Sciences, University of Oxford, Oxford, Oxfordshire, United Kingdom
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Hilda Tateossian ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: h.tateossian@har.mrc.ac.uk(HT); s.brown@har.mrc.ac.uk(SDMB)
¶‡ The authors are joint senior authors on this work.
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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Steve D. M. Brown
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: h.tateossian@har.mrc.ac.uk(HT); s.brown@har.mrc.ac.uk(SDMB)
¶‡ The authors are joint senior authors on this work.
Affiliation Mammalian Genetics Unit, MRC Harwell Institute, Harwell, Oxfordshire, United Kingdom
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A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways
- Michael Crompton,
- Tom Purnell,
- Hayley E. Tyrer,
- Andrew Parker,
- Greg Ball,
- Rachel E. Hardisty-Hughes,
- Richard Gale,
- Debbie Williams,
- Charlotte H. Dean,
- Michelle M. Simon
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- Published: August 14, 2017
- https://doi.org/10.1371/journal.pgen.1006969