Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression

• Minghui Yue,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft

  Affiliations Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• Akiyo Ogawa,

  Roles Formal analysis, Investigation

  Affiliation Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

  ⨯
• Norishige Yamada,

  Roles Resources

  Affiliations Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• John Lalith Charles Richard,

  Roles Resources

  Affiliations Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

  http://orcid.org/0000-0002-1186-6390

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• Artem Barski,

  Roles Formal analysis, Funding acquisition, Software

  Affiliations Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America, Division of Allergy & Immunology and Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

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• Yuya Ogawa

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: yuya.ogawa@cchmc.org

  Affiliations Division of Reproductive Sciences, Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

  http://orcid.org/0000-0003-4416-7753

  ⨯