Human mutations in integrator complex subunits link transcriptome integrity to brain development

• Renske Oegema ,

  Contributed equally to this work with: Renske Oegema, David Baillat

  Current address: University Medical Center Utrecht, The Netherlands

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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• David Baillat ,

  Contributed equally to this work with: Renske Oegema, David Baillat

  Affiliation Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston TX, United States of America

  http://orcid.org/0000-0001-9794-374X

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• Rachel Schot,

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

  http://orcid.org/0000-0001-9578-4095

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• Leontine M. van Unen,

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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• Alice Brooks,

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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• Sima Kheradmand Kia,

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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• A. Jeannette M. Hoogeboom,

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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• Zheng Xia,

  Affiliations Division of Biostatistics, Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, United States of America, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States of America

  http://orcid.org/0000-0003-3364-8324

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• Wei Li,

  Affiliations Division of Biostatistics, Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, United States of America, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States of America

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• Matteo Cesaroni,

  Affiliation The Fels Institute, Temple University School of Medicine, Philadelphia, PA, United States of America

  http://orcid.org/0000-0002-6377-8157

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• Maarten H. Lequin,

  Current address: University Medical Center Utrecht, The Netherlands

  Affiliation Department of Pediatric Radiology, Erasmus MC- Sophia, University Medical Center Rotterdam, The Netherlands

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• Marjon van Slegtenhorst,

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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• William B. Dobyns,

  Affiliation Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, United States of America

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• Irenaeus F. M. de Coo,

  Affiliation Department of Neurology, Erasmus MC- Sophia, University Medical Center Rotterdam, The Netherlands

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• Frans W. Verheijen,

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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• Andreas Kremer,

  Affiliation Department of Bioinformatics, Erasmus MC, University Medical Center Rotterdam, The Netherlands

  http://orcid.org/0000-0003-1466-0600

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• Peter J. van der Spek,

  Affiliation Department of Bioinformatics, Erasmus MC, University Medical Center Rotterdam, The Netherlands

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• Daphne Heijsman,

  Affiliations Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands, Department of Bioinformatics, Erasmus MC, University Medical Center Rotterdam, The Netherlands

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• Eric J. Wagner ,

  * E-mail: g.mancini@erasmusmc.nl (GMSM); ejwagner@utmb.edu (EJW)

  ¶‡ EJW and MF also contributed equally to this work.

  Affiliation Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston TX, United States of America

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• Maarten Fornerod ,

  ¶‡ EJW and MF also contributed equally to this work.

  Affiliation Department of Pediatric Oncology and Biochemistry, Erasmus MC, University Medical Center Rotterdam, The Netherlands

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•  [ ... ],
• Grazia M. S. Mancini

  * E-mail: g.mancini@erasmusmc.nl (GMSM); ejwagner@utmb.edu (EJW)

  Affiliation Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands

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