Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis

Daffolyn Rachael Fels Elliott; Juliane Perner; Xiaodun Li; Martyn F. Symmons; Brett Verstak; Matthew Eldridge; Lawrence Bower; Maria O’Donovan; Nick J. Gay; the OCCAMS Consortium; Rebecca C. Fitzgerald

doi:10.1371/journal.pgen.1006808

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Open Access

Peer-reviewed

Research Article

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis

Daffolyn Rachael Fels Elliott ,

¶‡These are joint first authors on this work.

Affiliation MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Juliane Perner ,

¶‡These are joint first authors on this work.

Affiliation Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom
⨯
Xiaodun Li,

Affiliation MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Martyn F. Symmons,

Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Brett Verstak,

Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Matthew Eldridge,

Affiliation Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom

http://orcid.org/0000-0002-5799-8911

⨯
Lawrence Bower,

Affiliation Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom
⨯
Maria O’Donovan,

Affiliation Department of Histopathology, Cambridge University Hospital NHS Trust, Cambridge, United Kingdom
⨯
Nick J. Gay,

Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

http://orcid.org/0000-0002-2782-7169

⨯
the OCCAMS Consortium ,

¶OCCAMS is a UK-wide consortium supporting the International Cancer Genome Consortium (ICGC), please see acknowledgments for full list of contributors
⨯
Rebecca C. Fitzgerald

* E-mail: RCF29@MRC-CU.cam.ac.uk

Affiliation MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis

Daffolyn Rachael Fels Elliott,
Juliane Perner,
Xiaodun Li,
Martyn F. Symmons,
Brett Verstak,
Matthew Eldridge,
Lawrence Bower,
Maria O’Donovan,
Nick J. Gay,
the OCCAMS Consortium

Published: May 22, 2017
https://doi.org/10.1371/journal.pgen.1006808

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Mutation databases
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Toll-like receptors
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Colorectal cancer
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Esophageal cancer
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Gastrointestinal cancers
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Gastric cancer
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Immune receptor signaling
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Lung and intrathoracic tumors
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