Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene

Haruhiko Fujihira; Yuki Masahara-Negishi; Masaru Tamura; Chengcheng Huang; Yoichiro Harada; Shigeharu Wakana; Daisuke Takakura; Nana Kawasaki; Naoyuki Taniguchi; Gen Kondoh; Tadashi Yamashita; Yoko Funakoshi; Tadashi Suzuki

doi:10.1371/journal.pgen.1006696

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Open Access

Peer-reviewed

Research Article

Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene

Haruhiko Fujihira,

Affiliation Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan
⨯
Yuki Masahara-Negishi,

Affiliation Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan
⨯
Masaru Tamura,

Affiliation Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, BioResourse Center, RIKEN, Ibaraki, Japan
⨯
Chengcheng Huang,

Affiliation Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan
⨯
Yoichiro Harada,

Affiliation Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan
⨯
Shigeharu Wakana,

Affiliation Technology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, BioResourse Center, RIKEN, Ibaraki, Japan
⨯
Daisuke Takakura,

Affiliation Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan
⨯
Nana Kawasaki,

Affiliation Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan
⨯
Naoyuki Taniguchi,

Affiliation Disease Glycomics Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan
⨯
Gen Kondoh,

Affiliation Laboratory of Integrative Biological Science, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan
⨯
Tadashi Yamashita,

Affiliation Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Kanagawa, Japan
⨯
Yoko Funakoshi,

Affiliation Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan
⨯
Tadashi Suzuki

* E-mail: tsuzuki_gm@riken.jp

Affiliation Glycometabolome Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, Global Research Cluster, RIKEN, Saitama, Japan
⨯

Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene

Haruhiko Fujihira,
Yuki Masahara-Negishi,
Masaru Tamura,
Chengcheng Huang,
Yoichiro Harada,
Shigeharu Wakana,
Daisuke Takakura,
Nana Kawasaki,
Naoyuki Taniguchi,
Gen Kondoh

Published: April 20, 2017
https://doi.org/10.1371/journal.pgen.1006696

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