Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip

Madapura M. Pradeepa; Fionnuala McKenna; Gillian C. A. Taylor; Hemant Bengani; Graeme R. Grimes; Andrew J. Wood; Shipra Bhatia; Wendy A. Bickmore

doi:10.1371/journal.pgen.1006677

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Open Access

Peer-reviewed

Research Article

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip

Madapura M. Pradeepa ,

* E-mail: pmadap@essex.ac.uk (MMP); Wendy.Bickmore@igmm.ed.ac.uk (WAB)

Affiliations MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at University of Edinburgh, Edinburgh, United Kingdom, School of biological sciences, University of Essex, Colchester, United Kingdom
⨯
Fionnuala McKenna,

Affiliation School of biological sciences, University of Essex, Colchester, United Kingdom
⨯
Gillian C. A. Taylor,

Affiliation MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at University of Edinburgh, Edinburgh, United Kingdom
⨯
Hemant Bengani,

Affiliation MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at University of Edinburgh, Edinburgh, United Kingdom
⨯
Graeme R. Grimes,

Affiliation MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at University of Edinburgh, Edinburgh, United Kingdom
⨯
Andrew J. Wood,

Affiliation MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at University of Edinburgh, Edinburgh, United Kingdom

http://orcid.org/0000-0002-0653-2070

⨯
Shipra Bhatia,

Affiliation MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at University of Edinburgh, Edinburgh, United Kingdom
⨯
Wendy A. Bickmore

* E-mail: pmadap@essex.ac.uk (MMP); Wendy.Bickmore@igmm.ed.ac.uk (WAB)

Affiliation MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at University of Edinburgh, Edinburgh, United Kingdom

http://orcid.org/0000-0001-6660-7735

⨯

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip

Madapura M. Pradeepa,
Fionnuala McKenna,
Gillian C. A. Taylor,
Hemant Bengani,
Graeme R. Grimes,
Andrew J. Wood,
Shipra Bhatia,
Wendy A. Bickmore

Published: April 6, 2017
https://doi.org/10.1371/journal.pgen.1006677
See the preprint

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Long non-coding RNA
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Guide RNA
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