Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci

• Joana Rolo,

  Affiliations Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal, Laboratory of Bacterial Evolution and Molecular Epidemiology, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal

  http://orcid.org/0000-0002-5291-212X

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• Peder Worning,

  Affiliation MRSA Knowledge Center, Department of Clinical Microbiology, Hvidovre Hospital, Hvidovre, Denmark

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• Jesper Boye Nielsen,

  Affiliation MRSA Knowledge Center, Department of Clinical Microbiology, Hvidovre Hospital, Hvidovre, Denmark

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• Rita Sobral,

  Affiliation UCIBIO-REQUIMTE, Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Caparica, Portugal

  http://orcid.org/0000-0003-4533-7531

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• Rory Bowden,

  Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom

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• Ons Bouchami,

  Affiliations Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal, Laboratory of Bacterial Evolution and Molecular Epidemiology, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal

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• Peter Damborg,

  Affiliation Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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• Luca Guardabassi,

  Affiliations Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, Department of Biomedical Sciences, Ross University School of Veterinary Medicine, Basseterre, St Kitts, West Indies

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• Vincent Perreten,

  Affiliation Department of Molecular Epidemiology and Infectious Diseases, Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland

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• Henrik Westh,

  Affiliations MRSA Knowledge Center, Department of Clinical Microbiology, Hvidovre Hospital, Hvidovre, Denmark, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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• Alexander Tomasz,

  Affiliation Laboratory of Microbiology and Infectious Diseases, The Rockefeller University, New York, United States of America

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• Hermínia de Lencastre,

  Affiliations Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal, Laboratory of Microbiology and Infectious Diseases, The Rockefeller University, New York, United States of America

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• Maria Miragaia

  * E-mail: miragaia@itqb.unl.pt

  Affiliations Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal, Laboratory of Bacterial Evolution and Molecular Epidemiology, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal

  http://orcid.org/0000-0002-1323-7184

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