CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy

Janelle Mapes; Quanxi Li; Athilakshmi Kannan; Lavanya Anandan; Mary Laws; John P. Lydon; Indrani C. Bagchi; Milan K. Bagchi

doi:10.1371/journal.pgen.1006654

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Peer-reviewed

Research Article

CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy

Janelle Mapes ,

¶‡ These authors share first authorship on this work

Affiliation Department of Molecular and Integrative Physiology, University of Illinois Urbana/Champaign, Urbana, IL, United States of America

http://orcid.org/0000-0002-9609-1255

⨯
Quanxi Li ,

¶‡ These authors share first authorship on this work

Affiliation Department of Comparative Biosciences, University of Illinois Urbana/Champaign, Urbana, IL, United States of America
⨯
Athilakshmi Kannan,

Affiliation Department of Comparative Biosciences, University of Illinois Urbana/Champaign, Urbana, IL, United States of America
⨯
Lavanya Anandan,

Affiliation Department of Molecular and Integrative Physiology, University of Illinois Urbana/Champaign, Urbana, IL, United States of America
⨯
Mary Laws,

Affiliation Department of Comparative Biosciences, University of Illinois Urbana/Champaign, Urbana, IL, United States of America

http://orcid.org/0000-0001-5140-488X

⨯
John P. Lydon,

Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States of America
⨯
Indrani C. Bagchi ,

* E-mail: ibagchi@illinois.edu (ICB); mbagchi@life.illinois.edu (MKB)

Affiliation Department of Comparative Biosciences, University of Illinois Urbana/Champaign, Urbana, IL, United States of America
⨯
Milan K. Bagchi

* E-mail: ibagchi@illinois.edu (ICB); mbagchi@life.illinois.edu (MKB)

Affiliation Department of Molecular and Integrative Physiology, University of Illinois Urbana/Champaign, Urbana, IL, United States of America
⨯

CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy

Janelle Mapes,
Quanxi Li,
Athilakshmi Kannan,
Lavanya Anandan,
Mary Laws,
John P. Lydon,
Indrani C. Bagchi,
Milan K. Bagchi

Published: March 9, 2017
https://doi.org/10.1371/journal.pgen.1006654

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Mammary glands
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Pregnancy
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Lactation
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Epithelial cells
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Phosphorylation
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STAT signaling
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Epithelium
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Gene expression
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