SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer

Shruthy Suresh; Deniz Durakoglugil; Xiaorong Zhou; Bokai Zhu; Sarah A. Comerford; Chao Xing; Xian-Jin Xie; Brian York; Kathryn A. O’Donnell

doi:10.1371/journal.pgen.1006650

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Open Access

Peer-reviewed

Research Article

SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer

Shruthy Suresh,

Affiliation Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, United States of America
⨯
Deniz Durakoglugil,

Affiliation Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, United States of America

http://orcid.org/0000-0003-2393-7528

⨯
Xiaorong Zhou,

Affiliations Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, United States of America, Department of Immunology, Nantong University School of Medicine, Nantong, China
⨯
Bokai Zhu,

Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States of America

http://orcid.org/0000-0003-0827-5757

⨯
Sarah A. Comerford,

Affiliation Department of Molecular Genetics, UT Southwestern Medical Center, Dallas, TX, United States of America
⨯
Chao Xing,

Affiliations Department of Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, United States of America, McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX, United States of America
⨯
Xian-Jin Xie,

Affiliations Department of Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, United States of America, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, United States of America

http://orcid.org/0000-0002-5698-0330

⨯
Brian York,

Affiliations Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States of America, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, United States of America
⨯
Kathryn A. O’Donnell

* E-mail: Kathryn.ODonnell@UTSouthwestern.edu

Affiliations Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX, United States of America, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, United States of America
⨯

SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer

Shruthy Suresh,
Deniz Durakoglugil,
Xiaorong Zhou,
Bokai Zhu,
Sarah A. Comerford,
Chao Xing,
Xian-Jin Xie,
Brian York,
Kathryn A. O’Donnell

Published: March 8, 2017
https://doi.org/10.1371/journal.pgen.1006650

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