A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets

• Jaleal S. Sanjak ,

  * E-mail: jsanjak@uci.edu (JSS); krthornt@uci.edu (KRT)

  Affiliations Department of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, California, USA, Center for Complex Biological Systems, University of California, Irvine, Irvine, California, USA

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• Anthony D. Long,

  Affiliations Department of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, California, USA, Center for Complex Biological Systems, University of California, Irvine, Irvine, California, USA

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• Kevin R. Thornton

  * E-mail: jsanjak@uci.edu (JSS); krthornt@uci.edu (KRT)

  Affiliations Department of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, California, USA, Center for Complex Biological Systems, University of California, Irvine, Irvine, California, USA

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