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Open Access
Peer-reviewed
Research Article
Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis
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Marcin J. Skwark ,
Contributed equally to this work with: Marcin J. Skwark, Nicholas J. Croucher
Affiliation Department of Chemistry, Vanderbilt University, Nashville, TN, United States of America
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Nicholas J. Croucher ,
Contributed equally to this work with: Marcin J. Skwark, Nicholas J. Croucher
Affiliation Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
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Santeri Puranen,
Affiliation Department of Computer Science, Aalto University, Espoo, Finland
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Claire Chewapreecha,
Affiliation Department of Medicine, University of Cambridge, Cambridge, United Kingdom
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Maiju Pesonen,
Affiliation Department of Computer Science, Aalto University, Espoo, Finland
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Ying Ying Xu,
Affiliation Department of Computer Science, Aalto University, Espoo, Finland
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Paul Turner,
Affiliations Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand, Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
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Simon R. Harris,
Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Stephen B. Beres,
Affiliation Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, and Houston Methodist Hospital, Houston, Texas, United States of America
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James M. Musser,
Affiliations Center for Molecular and Translational Human Infectious Diseases Research, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, and Houston Methodist Hospital, Houston, Texas, United States of America, Departments of Pathology and Laboratory Medicine and Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Julian Parkhill,
Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Stephen D. Bentley,
Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Erik Aurell ,
* E-mail: jukka.corander@medisin.uio.no (JC); eaurell@kth.se (EA)
Affiliations Department of Computational Biology, KTH–Royal Institute of Technology, Stockholm, Sweden, Departments of Applied Physics and Computer Science, Aalto University, Espoo, Finland, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing, China
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Jukka Corander
* E-mail: jukka.corander@medisin.uio.no (JC); eaurell@kth.se (EA)
Affiliations Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom, Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland, Department of Biostatistics, University of Oslo, Oslo, Norway, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
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Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis
- Marcin J. Skwark,
- Nicholas J. Croucher,
- Santeri Puranen,
- Claire Chewapreecha,
- Maiju Pesonen,
- Ying Ying Xu,
- Paul Turner,
- Simon R. Harris,
- Stephen B. Beres,
- James M. Musser
- Published: February 16, 2017
- https://doi.org/10.1371/journal.pgen.1006508
- See the preprint