Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon Regeneration

Li Chen; Derek M. Nye; Michelle C. Stone; Alexis T. Weiner; Kyle W. Gheres; Xin Xiong; Catherine A. Collins; Melissa M. Rolls

doi:10.1371/journal.pgen.1006503

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Peer-reviewed

Research Article

Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon Regeneration

Li Chen,

Affiliation Huck Institutes of the Life Sciences, and Biochemistry and Molecular Biology,The Pennsylvania State University, University Park, Pennsylvania, United States of America
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Derek M. Nye,

Affiliation Huck Institutes of the Life Sciences, and Biochemistry and Molecular Biology,The Pennsylvania State University, University Park, Pennsylvania, United States of America
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Michelle C. Stone,

Affiliation Huck Institutes of the Life Sciences, and Biochemistry and Molecular Biology,The Pennsylvania State University, University Park, Pennsylvania, United States of America
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Alexis T. Weiner,

Affiliation Huck Institutes of the Life Sciences, and Biochemistry and Molecular Biology,The Pennsylvania State University, University Park, Pennsylvania, United States of America
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Kyle W. Gheres,

Affiliation Huck Institutes of the Life Sciences, and Biochemistry and Molecular Biology,The Pennsylvania State University, University Park, Pennsylvania, United States of America
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Xin Xiong,

Affiliation Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America
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Catherine A. Collins,

Affiliation Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America
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Melissa M. Rolls

* E-mail: mur22@psu.edu

Affiliation Huck Institutes of the Life Sciences, and Biochemistry and Molecular Biology,The Pennsylvania State University, University Park, Pennsylvania, United States of America

http://orcid.org/0000-0002-5021-4360

⨯

Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon Regeneration

Li Chen,
Derek M. Nye,
Michelle C. Stone,
Alexis T. Weiner,
Kyle W. Gheres,
Xin Xiong,
Catherine A. Collins,
Melissa M. Rolls

Published: December 6, 2016
https://doi.org/10.1371/journal.pgen.1006503

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Neuronal dendrites
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Axons
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Neurons
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Mitochondria
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RNA interference
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Regeneration
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Microtubule dynamics
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Nerve regeneration
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