Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia

Shiran Naftelberg; Ziv Abramovitch; Shani Gluska; Sivan Yannai; Yuvraj Joshi; Maya Donyo; Keren Ben-Yaakov; Tal Gradus; Jonathan Zonszain; Chen Farhy; Ruth Ashery-Padan; Eran Perlson; Gil Ast

doi:10.1371/journal.pgen.1006486

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Open Access

Peer-reviewed

Research Article

Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia

Shiran Naftelberg,

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Ziv Abramovitch,

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Shani Gluska,

Affiliation Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Sivan Yannai,

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Yuvraj Joshi,

Affiliation Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Maya Donyo,

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Keren Ben-Yaakov,

Affiliation Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Tal Gradus,

Affiliation Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Jonathan Zonszain,

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Chen Farhy,

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Ruth Ashery-Padan,

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Eran Perlson ,

Contributed equally to this work with: Eran Perlson, Gil Ast

* E-mail: eranpe@post.tau.ac.il (EP); gilast@post.tau.ac.il (GA)

Affiliation Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Gil Ast

Contributed equally to this work with: Eran Perlson, Gil Ast

* E-mail: eranpe@post.tau.ac.il (EP); gilast@post.tau.ac.il (GA)

Affiliation Department of Human Molecular Genetics and Biochemestry. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯

Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia

Shiran Naftelberg,
Ziv Abramovitch,
Shani Gluska,
Sivan Yannai,
Yuvraj Joshi,
Maya Donyo,
Keren Ben-Yaakov,
Tal Gradus,
Jonathan Zonszain,
Chen Farhy

Published: December 20, 2016
https://doi.org/10.1371/journal.pgen.1006486

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