GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis

Guillaume Jannot; Pascale Michaud; Miguel Quévillon Huberdeau; Louis Morel-Berryman; James A. Brackbill; Sandra Piquet; Katherine McJunkin; Kotaro Nakanishi; Martin J. Simard

doi:10.1371/journal.pgen.1006484

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Peer-reviewed

Research Article

GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis

Guillaume Jannot,

Current address: Epigenetics and Cell Fate, Centre national de la recherche scientifique (UMR 7126), Université Paris Diderot (Sorbonne Paris Cité), Paris, France

Affiliations St-Patrick Research Group in Basic Oncology, CHU de Québec-Université Laval Research Centre (Hôtel-Dieu de Québec), Quebec City, Québec, Canada, Laval University Cancer Research Centre, Quebec City, Québec, Canada
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Pascale Michaud,

Affiliations St-Patrick Research Group in Basic Oncology, CHU de Québec-Université Laval Research Centre (Hôtel-Dieu de Québec), Quebec City, Québec, Canada, Laval University Cancer Research Centre, Quebec City, Québec, Canada
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Miguel Quévillon Huberdeau,

Affiliations St-Patrick Research Group in Basic Oncology, CHU de Québec-Université Laval Research Centre (Hôtel-Dieu de Québec), Quebec City, Québec, Canada, Laval University Cancer Research Centre, Quebec City, Québec, Canada
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Louis Morel-Berryman,

Affiliations St-Patrick Research Group in Basic Oncology, CHU de Québec-Université Laval Research Centre (Hôtel-Dieu de Québec), Quebec City, Québec, Canada, Laval University Cancer Research Centre, Quebec City, Québec, Canada
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James A. Brackbill,

Affiliation Department of Chemistry & Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
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Sandra Piquet,

Affiliations St-Patrick Research Group in Basic Oncology, CHU de Québec-Université Laval Research Centre (Hôtel-Dieu de Québec), Quebec City, Québec, Canada, Laval University Cancer Research Centre, Quebec City, Québec, Canada

http://orcid.org/0000-0002-5745-9862

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Katherine McJunkin,

Affiliation Program in Molecular Medicine, RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
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Kotaro Nakanishi,

Affiliation Department of Chemistry & Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
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Martin J. Simard

* E-mail: Martin.Simard@crchudequebec.ulaval.ca

Affiliations St-Patrick Research Group in Basic Oncology, CHU de Québec-Université Laval Research Centre (Hôtel-Dieu de Québec), Quebec City, Québec, Canada, Laval University Cancer Research Centre, Quebec City, Québec, Canada
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GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis

Guillaume Jannot,
Pascale Michaud,
Miguel Quévillon Huberdeau,
Louis Morel-Berryman,
James A. Brackbill,
Sandra Piquet,
Katherine McJunkin,
Kotaro Nakanishi,
Martin J. Simard

Published: December 9, 2016
https://doi.org/10.1371/journal.pgen.1006484

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MicroRNAs
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Caenorhabditis elegans
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Gene expression
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Gene silencing
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Protein interactions
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Immunoprecipitation
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Embryogenesis
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Genetically modified animals
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