A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

Open Access

Peer-reviewed

Research Article

Salahuddin Syed,

Affiliations Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, United States of America, Graduate Program in Cellular and Molecular Biology, University of South Florida, Tampa, Florida, United States of America
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Claus Desler,

Affiliation Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
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Lene J. Rasmussen,

Affiliation Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
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Kristina H. Schmidt

* E-mail: kschmidt@usf.edu

Affiliations Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, United States of America, Cancer Biology and Evolution Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America
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DNA replication
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Synthesis phase
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Chromatin
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DNA damage
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DNA synthesis
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DNA repair
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Yeast
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Helicases
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