Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse

Federica Federici; Aristea Magaraki; Evelyne Wassenaar; Catherina J. H. van Veen-Buurman; Christine van de Werken; Esther B Baart; Joop S. E. Laven; J Anton Grootegoed; Joost Gribnau; Willy M Baarends

doi:10.1371/journal.pgen.1006358

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Open Access

Peer-reviewed

Research Article

Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse

Federica Federici ,

Contributed equally to this work with: Federica Federici, Aristea Magaraki

Affiliation Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
Aristea Magaraki ,

Contributed equally to this work with: Federica Federici, Aristea Magaraki

Affiliation Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
Evelyne Wassenaar,

Affiliation Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
Catherina J. H. van Veen-Buurman,

Affiliation Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
Christine van de Werken,

Affiliation Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
Esther B Baart,

Affiliation Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

http://orcid.org/0000-0002-2611-3148

⨯
Joop S. E. Laven,

Affiliation Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
J Anton Grootegoed,

Affiliation Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
Joost Gribnau,

Affiliation Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
⨯
Willy M Baarends

* E-mail: w.baarends@erasmusmc.nl

Affiliation Department of Developmental Biology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands

http://orcid.org/0000-0002-9179-850X

⨯

Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse

Federica Federici,
Aristea Magaraki,
Evelyne Wassenaar,
Catherina J. H. van Veen-Buurman,
Christine van de Werken,
Esther B Baart,
Joop S. E. Laven,
J Anton Grootegoed,
Joost Gribnau,
Willy M Baarends

Published: October 7, 2016
https://doi.org/10.1371/journal.pgen.1006358

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