Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy

• Stacey D. Wagner,

  Affiliation Department of Chemistry and Biochemistry, Institute of Molecular Biology, University of Oregon, Eugene, Oregon, United States of America

  http://orcid.org/0000-0003-3992-0798

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• Adam J. Struck,

  Affiliation Department of Chemistry and Biochemistry, Institute of Molecular Biology, University of Oregon, Eugene, Oregon, United States of America

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• Riti Gupta,

  Affiliation Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Dylan R. Farnsworth,

  Affiliation Department of Biology, Institute of Molecular Biology, University of Oregon, Eugene, Oregon, United States of America

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• Amy E. Mahady,

  Affiliation Department of Chemistry and Biochemistry, Institute of Molecular Biology, University of Oregon, Eugene, Oregon, United States of America

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• Katy Eichinger,

  Affiliation Department of Neurology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Charles A. Thornton,

  Affiliation Department of Neurology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Eric T. Wang ,

  * E-mail: eric.t.wang@ufl.edu (ETW); aberglund@ufl.edu (JAB)

  Affiliations Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biochemistry & Molecular Biology, Center for NeuroGenetics, University of Florida, Gainesville, Florida, United States of America

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• J. Andrew Berglund

  * E-mail: eric.t.wang@ufl.edu (ETW); aberglund@ufl.edu (JAB)

  Affiliations Department of Chemistry and Biochemistry, Institute of Molecular Biology, University of Oregon, Eugene, Oregon, United States of America, Department of Biochemistry & Molecular Biology, Center for NeuroGenetics, University of Florida, Gainesville, Florida, United States of America

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