A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/M

• Sriram Vijayraghavan ,

  Contributed equally to this work with: Sriram Vijayraghavan, Feng-Ling Tsai

  Current address: Department of Molecular Genetics and Microbiology, Duke University, Duke University Medical Center, Durham, NC

  Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Feng-Ling Tsai ,

  Contributed equally to this work with: Sriram Vijayraghavan, Feng-Ling Tsai

  Current address: QC Microbiology Laboratory, Impax Laboratories Inc., Jhunan, Miao-Li County 350, Taiwan, R.O.C.

  Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Anthony Schwacha

  * E-mail: schwacha@pitt.edu

  Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  http://orcid.org/0000-0002-9664-9503

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