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Open Access
Peer-reviewed
Research Article
Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination
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Tongchao Li,
Affiliation Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Junkai Fan ,
Contributed equally to this work with: Junkai Fan, Bernardo Blanco-Sánchez
Affiliation Markey Cancer Center and Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America
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Bernardo Blanco-Sánchez ,
Contributed equally to this work with: Junkai Fan, Bernardo Blanco-Sánchez
Affiliation Institute of Neuroscience, University of Oregon, Eugene, Oregon, United States of America
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Nikolaos Giagtzoglou,
Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital, Houston, Texas, United States of America
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Guang Lin,
Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
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Shinya Yamamoto,
Affiliations Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital, Houston, Texas, United States of America
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Manish Jaiswal,
Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America
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Kuchuan Chen,
Affiliation Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America
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Jie Zhang,
Affiliation Markey Cancer Center and Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America
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Wei Wei,
Affiliations Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, United States of America
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Michael T. Lewis,
Affiliations Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, United States of America
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Andrew K. Groves,
Affiliations Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America
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Monte Westerfield,
Affiliation Institute of Neuroscience, University of Oregon, Eugene, Oregon, United States of America
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Jianhang Jia,
Affiliation Markey Cancer Center and Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America
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Hugo J. Bellen
* E-mail: hbellen@bcm.edu
Affiliations Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital, Houston, Texas, United States of America, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America, Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America
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Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination
- Tongchao Li,
- Junkai Fan,
- Bernardo Blanco-Sánchez,
- Nikolaos Giagtzoglou,
- Guang Lin,
- Shinya Yamamoto,
- Manish Jaiswal,
- Kuchuan Chen,
- Jie Zhang,
- Wei Wei
- Published: May 19, 2016
- https://doi.org/10.1371/journal.pgen.1006054