Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation

Ana Bratic; Paula Clemente; Javier Calvo-Garrido; Camilla Maffezzini; Andrea Felser; Rolf Wibom; Anna Wedell; Christoph Freyer; Anna Wredenberg

doi:10.1371/journal.pgen.1006028

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Peer-reviewed

Research Article

Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation

Ana Bratic ,

Contributed equally to this work with: Ana Bratic, Paula Clemente

Affiliation Department of Mitochondrial Biology, Max Planck Institute for Biology of Ageing, Cologne, Germany
⨯
Paula Clemente ,

Contributed equally to this work with: Ana Bratic, Paula Clemente

Affiliation Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯
Javier Calvo-Garrido,

Affiliation Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
⨯
Camilla Maffezzini,

Affiliation Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯
Andrea Felser,

Affiliation Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯
Rolf Wibom,

Affiliations Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden, Centre for Inherited Metabolic Diseases, Karolinska University Hospital, Stockholm, Sweden
⨯
Anna Wedell,

Affiliations Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden, Centre for Inherited Metabolic Diseases, Karolinska University Hospital, Stockholm, Sweden
⨯
Christoph Freyer ,

* E-mail: christoph.freyer@ki.se (CF); anna.wredenberg@ki.se (AW)

Affiliations Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden, Centre for Inherited Metabolic Diseases, Karolinska University Hospital, Stockholm, Sweden
⨯
Anna Wredenberg

* E-mail: christoph.freyer@ki.se (CF); anna.wredenberg@ki.se (AW)

Affiliations Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden, Centre for Inherited Metabolic Diseases, Karolinska University Hospital, Stockholm, Sweden
⨯

Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation

Ana Bratic,
Paula Clemente,
Javier Calvo-Garrido,
Camilla Maffezzini,
Andrea Felser,
Rolf Wibom,
Anna Wedell,
Christoph Freyer,
Anna Wredenberg

Published: May 13, 2016
https://doi.org/10.1371/journal.pgen.1006028

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Mitochondria
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Polyadenylation
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Larvae
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Messenger RNA
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RNA interference
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Transfer RNA
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Cloning
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Drosophila melanogaster
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