Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

James E. Peters; Paul A. Lyons; James C. Lee; Arianne C. Richard; Mary D. Fortune; Paul J. Newcombe; Sylvia Richardson; Kenneth G. C. Smith

doi:10.1371/journal.pgen.1005908

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Open Access

Peer-reviewed

Research Article

Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

James E. Peters,

Affiliations Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, Cambridge Institute For Medical Research, University of Cambridge, Cambridge, United Kingdom, MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, United Kingdom
⨯
Paul A. Lyons,

Affiliations Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, Cambridge Institute For Medical Research, University of Cambridge, Cambridge, United Kingdom
⨯
James C. Lee,

Affiliations Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, Cambridge Institute For Medical Research, University of Cambridge, Cambridge, United Kingdom
⨯
Arianne C. Richard,

Affiliations Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, Cambridge Institute For Medical Research, University of Cambridge, Cambridge, United Kingdom, Immunoregulation Section, Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, United States of America
⨯
Mary D. Fortune,

Affiliations Cambridge Institute For Medical Research, University of Cambridge, Cambridge, United Kingdom, JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom
⨯
Paul J. Newcombe,

Affiliation MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, United Kingdom
⨯
Sylvia Richardson,

Affiliation MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, United Kingdom
⨯
Kenneth G. C. Smith

* E-mail: kgcs2@medschl.cam.ac.uk

Affiliations Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, Cambridge Institute For Medical Research, University of Cambridge, Cambridge, United Kingdom
⨯

Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

James E. Peters,
Paul A. Lyons,
James C. Lee,
Arianne C. Richard,
Mary D. Fortune,
Paul J. Newcombe,
Sylvia Richardson,
Kenneth G. C. Smith

Published: March 25, 2016
https://doi.org/10.1371/journal.pgen.1005908

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Single nucleotide polymorphisms
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