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Open Access
Peer-reviewed
Research Article
Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer
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Liyan Jiang ,
Contributed equally to this work with: Liyan Jiang, Jiaqi Huang, Brandon W. Higgs, Zhibin Hu, Zhan Xiao
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Jiaqi Huang ,
Contributed equally to this work with: Liyan Jiang, Jiaqi Huang, Brandon W. Higgs, Zhibin Hu, Zhan Xiao
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Brandon W. Higgs ,
Contributed equally to this work with: Liyan Jiang, Jiaqi Huang, Brandon W. Higgs, Zhibin Hu, Zhan Xiao
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Zhibin Hu ,
Contributed equally to this work with: Liyan Jiang, Jiaqi Huang, Brandon W. Higgs, Zhibin Hu, Zhan Xiao
Affiliation Department of Epidemiology and Biostatistics, Collaborative Innovation Center of Cancer Medicine, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, School of Public Health, Nanjing Medical University, Nanjing, China
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Zhan Xiao ,
Contributed equally to this work with: Liyan Jiang, Jiaqi Huang, Brandon W. Higgs, Zhibin Hu, Zhan Xiao
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Xin Yao,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Sarah Conley,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Haihong Zhong,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Zheng Liu,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Philip Brohawn,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Dong Shen,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Song Wu,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Xiaoxiao Ge,
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Yue Jiang,
Affiliation Department of Epidemiology and Biostatistics, Collaborative Innovation Center of Cancer Medicine, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, School of Public Health, Nanjing Medical University, Nanjing, China
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Yizhuo Zhao,
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Yuqing Lou,
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Chris Morehouse,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Wei Zhu,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Yinong Sebastian,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Meggan Czapiga,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Vaheh Oganesyan,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Haihua Fu,
Affiliation Asia & Emerging Markets iMed, AstraZeneca R&D, Shanghai, China
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Yanjie Niu,
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Wei Zhang,
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Katie Streicher,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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David Tice,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Heng Zhao,
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Meng Zhu,
Affiliation Department of Epidemiology and Biostatistics, Collaborative Innovation Center of Cancer Medicine, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, School of Public Health, Nanjing Medical University, Nanjing, China
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Lin Xu,
Affiliation Department of Epidemiology and Biostatistics, Collaborative Innovation Center of Cancer Medicine, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, School of Public Health, Nanjing Medical University, Nanjing, China
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Ronald Herbst,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Xinying Su,
Affiliation Asia & Emerging Markets iMed, AstraZeneca R&D, Shanghai, China
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Yi Gu,
Affiliation Asia & Emerging Markets iMed, AstraZeneca R&D, Shanghai, China
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Shyoung Li,
Affiliation Beijing Genomics Institute, Shenzhen GuangDong, China
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Lihua Huang,
Affiliation Beijing Genomics Institute, Shenzhen GuangDong, China
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Jianren Gu,
Affiliation Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Baohui Han,
Affiliation Department of Pulmonary, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Bahija Jallal,
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Hongbing Shen ,
* E-mail: hbshen@njmu.edu.cn (HS); oliver_67@yahoo.com (YY)
Affiliation Department of Epidemiology and Biostatistics, Collaborative Innovation Center of Cancer Medicine, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, School of Public Health, Nanjing Medical University, Nanjing, China
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Yihong Yao
* E-mail: hbshen@njmu.edu.cn (HS); oliver_67@yahoo.com (YY)
Affiliation Medimmune, Gaithersburg, Maryland, United States of America
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Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer
- Liyan Jiang,
- Jiaqi Huang,
- Brandon W. Higgs,
- Zhibin Hu,
- Zhan Xiao,
- Xin Yao,
- Sarah Conley,
- Haihong Zhong,
- Zheng Liu,
- Philip Brohawn
- Published: April 19, 2016
- https://doi.org/10.1371/journal.pgen.1005895