RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

Julia E. Draper; Patrycja Sroczynska; Olga Tsoulaki; Hui Sun Leong; Muhammad Z. H. Fadlullah; Crispin Miller; Valerie Kouskoff; Georges Lacaud

doi:10.1371/journal.pgen.1005814

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Peer-reviewed

Research Article

RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

Julia E. Draper,

Affiliation Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⨯
Patrycja Sroczynska,

Affiliations Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom, Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark, Centre for Epigenetics, University of Copenhagen, Copenhagen, Denmark
⨯
Olga Tsoulaki,

Affiliation Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⨯
Hui Sun Leong,

Affiliation Cancer Research UK Applied Computational Biology and Bioinformatics Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⨯
Muhammad Z. H. Fadlullah,

Affiliation Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⨯
Crispin Miller,

Affiliation Cancer Research UK Applied Computational Biology and Bioinformatics Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⨯
Valerie Kouskoff ,

* E-mail: Valerie.kouskoff@cruk.manchester.ac.uk (VK); georges.lacaud@cruk.manchester.ac.uk (GL)

Affiliation Cancer Research UK Stem Cell Haematopoiesis Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⨯
Georges Lacaud

* E-mail: Valerie.kouskoff@cruk.manchester.ac.uk (VK); georges.lacaud@cruk.manchester.ac.uk (GL)

Affiliation Cancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, United Kingdom
⨯

RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

Julia E. Draper,
Patrycja Sroczynska,
Olga Tsoulaki,
Hui Sun Leong,
Muhammad Z. H. Fadlullah,
Crispin Miller,
Valerie Kouskoff,
Georges Lacaud

Published: January 25, 2016
https://doi.org/10.1371/journal.pgen.1005814

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