Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

• Yunpeng Wang,

  Affiliations NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway, Department of Neurosciences, University of California, San Diego, La Jolla, California, United States of America, Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, California, United States of America

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• Wesley K. Thompson,

  Affiliation Department of Psychiatry, University of California, San Diego, La Jolla, California, United States of America

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• Andrew J. Schork,

  Affiliation Department of Cognitive Sciences, University of California at San Diego, La Jolla, California, United States of America

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• Dominic Holland,

  Affiliation Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, California, United States of America

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• Chi-Hua Chen,

  Affiliations Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, California, United States of America, Department of Radiology, University of California, San Diego, La Jolla, California, United States of America

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• Francesco Bettella,

  Affiliations NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

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• Rahul S. Desikan,

  Affiliations Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, California, United States of America, Department of Radiology, University of California, San Diego, La Jolla, California, United States of America

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• Wen Li,

  Affiliations NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

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• Aree Witoelar,

  Affiliations NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

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• Verena Zuber,

  Affiliations NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

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• Anna Devor,

  Affiliations Department of Neurosciences, University of California, San Diego, La Jolla, California, United States of America, Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, California, United States of America

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• Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium ,

  ¶Memberships of the Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium and Enhancing Neuro Imaging Genetics through Meta Analysis Consortium are provided in S1 Text.

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• Enhancing Neuro Imaging Genetics through Meta Analysis Consortium ,

  ¶Memberships of the Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium and Enhancing Neuro Imaging Genetics through Meta Analysis Consortium are provided in S1 Text.

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• Markus M. Nöthen,

  Affiliation Institute of Human Genetics, University of Bonn, Bonn, Germany

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• Marcella Rietschel,

  Affiliation Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Mannheim, Germany

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• Qiang Chen,

  Affiliation Lieber Institute for Brain Development, Baltimore, Maryland, United States of America

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• Thomas Werge,

  Affiliation Institute of Biological Psychiatry, MHC, Sct. Hans Hospital and University of Copenhagen, Copenhagen, Denmark

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• Sven Cichon,

  Affiliation Department of Biomedicine, University of Basel, Basel, Switzerland

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• Daniel R. Weinberger,

  Affiliation Lieber Institute for Brain Development, Baltimore, Maryland, United States of America

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• Srdjan Djurovic,

  Affiliations NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Department of Medical Genetics, Oslo University Hospital, Oslo, Norway

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• Michael O’Donovan,

  Affiliation MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom

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• Peter M. Visscher,

  Affiliations The Queensland Brain Institute, The University of Queensland, Brisbane, Australia, University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute (TRI), Brisbane, Australia

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• Ole A. Andreassen ,

  * E-mail: amdale@ucsd.edu (AMD); o.a.andreassen@medisin.uio.no (OAA)

  Affiliations NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway

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•  [ ... ],
• Anders M. Dale

  * E-mail: amdale@ucsd.edu (AMD); o.a.andreassen@medisin.uio.no (OAA)

  Affiliations Department of Neurosciences, University of California, San Diego, La Jolla, California, United States of America, Multimodal Imaging Laboratory, University of California at San Diego, La Jolla, California, United States of America, Department of Psychiatry, University of California, San Diego, La Jolla, California, United States of America, Department of Radiology, University of California, San Diego, La Jolla, California, United States of America

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