Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation

• Gongshi Bai,

  Affiliations Department of Biomedical Sciences, Cornell University, Ithaca, New York, United States of America, Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

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• Marcus B. Smolka,

  Affiliations Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America, Weill Institute for Cellular and Molecular Biology, Cornell University, Ithaca, New York, United States of America, Center for Vertebrate Genomics, Cornell University, Ithaca, New York, United States of America

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• John C. Schimenti

  * E-mail: jcs92@cornell.edu

  Affiliations Department of Biomedical Sciences, Cornell University, Ithaca, New York, United States of America, Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America, Center for Vertebrate Genomics, Cornell University, Ithaca, New York, United States of America

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