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Open Access
Peer-reviewed
Research Article
MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria
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Ilaria Dalla Rosa,
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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Yolanda Cámara,
Affiliations Laboratory of Mitochondrial Disorders, Vall d’Hebron Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Biomedical Network Research Centre on Rare Diseases, Instituto de Salud Carlos III, Madrid, Spain
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Romina Durigon,
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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Chloe F. Moss,
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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Sara Vidoni,
Affiliation MRC Mitochondrial Biology Unit, Wellcome Trust-MRC Building, Cambridge, United Kingdom
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Gokhan Akman,
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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Lilian Hunt,
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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Mark A. Johnson,
Affiliation MRC Mitochondrial Biology Unit, Wellcome Trust-MRC Building, Cambridge, United Kingdom
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Sarah Grocott,
Affiliation Mitochondrial Genetics Group, Nuffield Department of Obstetrics and Gynaecology, Women's Centre, The John Radcliffe Hospital, Oxford, United Kingdom
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Liya Wang,
Affiliation Department of Anatomy, Physiology and Biochemistry, The Swedish University of Agricultural Sciences, Biomedical Center, Uppsala, Sweden
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David R. Thorburn,
Affiliation Murdoch Childrens Research Institute and University of Melbourne Department of Paediatrics, Royal Children's Hospital, Flemington Road, Parkville, Victoria, Australia
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Michio Hirano,
Affiliation Department of Neurology, Columbia University Medical Center, New York, New York, United States of America
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Joanna Poulton,
Affiliation Mitochondrial Genetics Group, Nuffield Department of Obstetrics and Gynaecology, Women's Centre, The John Radcliffe Hospital, Oxford, United Kingdom
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Robert W. Taylor,
Affiliation Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom
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Greg Elgar,
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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Ramon Martí,
Affiliations Laboratory of Mitochondrial Disorders, Vall d’Hebron Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Biomedical Network Research Centre on Rare Diseases, Instituto de Salud Carlos III, Madrid, Spain
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Peter Voshol,
Affiliation Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom
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Ian J. Holt,
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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Antonella Spinazzola
* E-mail: antonella.spinazzola@crick.ac.uk
Affiliation MRC Mill Hill Laboratory, London, United Kingdom
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MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria
- Ilaria Dalla Rosa,
- Yolanda Cámara,
- Romina Durigon,
- Chloe F. Moss,
- Sara Vidoni,
- Gokhan Akman,
- Lilian Hunt,
- Mark A. Johnson,
- Sarah Grocott,
- Liya Wang
- Published: January 13, 2016
- https://doi.org/10.1371/journal.pgen.1005779