Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

Thomas Arbogast; Abdel-Mouttalib Ouagazzal; Claire Chevalier; Maksym Kopanitsa; Nurudeen Afinowi; Eugenia Migliavacca; Belinda S. Cowling; Marie-Christine Birling; Marie-France Champy; Alexandre Reymond; Yann Herault

doi:10.1371/journal.pgen.1005709

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Peer-reviewed

Research Article

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

Thomas Arbogast,

Affiliations Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France, Centre National de la Recherche Scientifique, UMR7104, Illkirch, France, Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France, Université de Strasbourg, Illkirch, France
⨯
Abdel-Mouttalib Ouagazzal,

Affiliations Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France, Centre National de la Recherche Scientifique, UMR7104, Illkirch, France, Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France, Université de Strasbourg, Illkirch, France
⨯
Claire Chevalier,

Affiliations Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France, Centre National de la Recherche Scientifique, UMR7104, Illkirch, France, Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France, Université de Strasbourg, Illkirch, France
⨯
Maksym Kopanitsa,

Affiliation Synome Ltd, Moneta Building, Babraham Research Campus, Cambridge, United Kingdom
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Nurudeen Afinowi,

Affiliation Synome Ltd, Moneta Building, Babraham Research Campus, Cambridge, United Kingdom
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Eugenia Migliavacca,

Affiliations Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland
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Belinda S. Cowling,

Affiliations Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France, Centre National de la Recherche Scientifique, UMR7104, Illkirch, France, Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France, Université de Strasbourg, Illkirch, France
⨯
Marie-Christine Birling,

Affiliation PHENOMIN, Institut Clinique de la Souris, ICS; CNRS, INSERM, University of Strasbourg, Illkirch-Graffenstaden, France
⨯
Marie-France Champy,

Affiliation PHENOMIN, Institut Clinique de la Souris, ICS; CNRS, INSERM, University of Strasbourg, Illkirch-Graffenstaden, France
⨯
Alexandre Reymond,

Affiliation Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland
⨯
Yann Herault

* E-mail: herault@igbmc.fr

Affiliations Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France, Centre National de la Recherche Scientifique, UMR7104, Illkirch, France, Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France, Université de Strasbourg, Illkirch, France, PHENOMIN, Institut Clinique de la Souris, ICS; CNRS, INSERM, University of Strasbourg, Illkirch-Graffenstaden, France
⨯

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

Thomas Arbogast,
Abdel-Mouttalib Ouagazzal,
Claire Chevalier,
Maksym Kopanitsa,
Nurudeen Afinowi,
Eugenia Migliavacca,
Belinda S. Cowling,
Marie-Christine Birling,
Marie-France Champy,
Alexandre Reymond

Published: February 12, 2016
https://doi.org/10.1371/journal.pgen.1005709

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