Comprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination

Xiaomin Dong; Kenian Chen; Raquel Cuevas-Diaz Duran; Yanan You; Steven A. Sloan; Ye Zhang; Shan Zong; Qilin Cao; Ben A. Barres; Jia Qian Wu

doi:10.1371/journal.pgen.1005669

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Peer-reviewed

Research Article

Comprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination

Xiaomin Dong,

Affiliations The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, United States of America, Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Houston, Texas, United States of America
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Kenian Chen,

Affiliations The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, United States of America, Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Houston, Texas, United States of America
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Raquel Cuevas-Diaz Duran,

Affiliations The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, United States of America, Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Houston, Texas, United States of America
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Yanan You,

Affiliations The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, United States of America, Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Houston, Texas, United States of America
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Steven A. Sloan,

Affiliation Department of Neurobiology, Stanford University School of Medicine, Stanford, California, United States of America
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Ye Zhang,

Affiliation Department of Neurobiology, Stanford University School of Medicine, Stanford, California, United States of America
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Shan Zong,

Affiliations The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, United States of America, Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Houston, Texas, United States of America
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Qilin Cao,

Affiliations The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, United States of America, Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Houston, Texas, United States of America
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Ben A. Barres,

Affiliation Department of Neurobiology, Stanford University School of Medicine, Stanford, California, United States of America
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Jia Qian Wu

* E-mail: jiaqian.wu@uth.tmc.edu

Affiliations The Vivian L. Smith Department of Neurosurgery, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, United States of America, Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Houston, Texas, United States of America
⨯

Comprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination

Xiaomin Dong,
Kenian Chen,
Raquel Cuevas-Diaz Duran,
Yanan You,
Steven A. Sloan,
Ye Zhang,
Shan Zong,
Qilin Cao,
Ben A. Barres,
Jia Qian Wu

Published: December 18, 2015
https://doi.org/10.1371/journal.pgen.1005669

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Long non-coding RNA
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Central nervous system
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Gene expression
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Transcriptional control
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Gene regulation
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Transcription factors
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Cell differentiation
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